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Everything here is reference information drawn from the research literature, not medical advice, and Lamduan is neither a doctor nor a pharmacist. Supplements are not medicines and do not replace anything a doctor has prescribed. If you take regular medication, are pregnant or breastfeeding, have liver or kidney disease, or have surgery coming up, speak to a pharmacist or doctor before starting anything on this page.
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The main mineral in bone. Absorption is best at 500 mg or less per dose, so a single 1,000 mg tablet wastes about half of itself.
🎯What it helps withModerate
Maintaining bone alongside vitamin D, particularly after menopause. Food first, then supplement only the gap.
⚗️Effect on hormonesNo human data
No effect on sex hormones. Blood calcium is governed by parathyroid hormone, which adjusts itself.
Weight and fat lossNo human data
Does not reduce fat.
🌙SleepNo human data
Nothing to do with sleep.
❤️Other health effectsStrong evidence
Bone, teeth, muscle contraction and nerve conduction.
📏Dose and ceiling
Commonly used: 500-1,000 mg per day
2,500 mg/day for ages 19-50 and 2,000 mg from 51 — IOM. This app warns at 2,000, the number that is safe at any age. Counts food as well.
When to take it
Take with food.
Caution
The WHI trial found 1,000 mg/day of supplemental calcium with vitamin D over 7 years raised kidney stone risk by 17%. There is also a contested signal that supplemental calcium, unlike dietary calcium, may raise cardiovascular risk. Remember to count chewable antacids — 200-400 mg each.
Interacts with medicines
Significantly reduces absorption of thyroid medicine — separate by 4 hours. Also reduces quinolone antibiotics and the HIV drug dolutegravir.